Detalhe da pesquisa
1.
Ablation of lysophosphatidic acid receptor 1 attenuates hypertrophic cardiomyopathy in a mouse model.
Proc Natl Acad Sci U S A
; 119(28): e2204174119, 2022 07 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-35787042
2.
Phthalazinone-based lactams and cyclic ureas as ROCK2 selective inhibitors.
Bioorg Med Chem Lett
; 88: 129304, 2023 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37119973
3.
LC/MS/MS-based quantitation of pig and human S100A1 protein in cardiac tissues: Application to gene therapy.
Anal Biochem
; 602: 113766, 2020 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32389692
4.
Identification of 5H-chromeno[3,4-c]pyridine and 6H-isochromeno[3,4-c]pyridine derivatives as potent and selective dual ROCK inhibitors.
Bioorg Med Chem Lett
; 30(21): 127474, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32805407
5.
Discovery of a phenylpyrazole amide ROCK inhibitor as a tool molecule for in vivo studies.
Bioorg Med Chem Lett
; 30(21): 127495, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32798651
6.
Benzothiazole-based compounds as potent endothelial lipase inhibitors.
Bioorg Med Chem Lett
; 29(20): 126673, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-31519373
7.
Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase.
Bioorg Med Chem Lett
; 29(15): 1918-1921, 2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31176700
8.
Discovery and synthesis of tetrahydropyrimidinedione-4-carboxamides as endothelial lipase inhibitors.
Bioorg Med Chem Lett
; 28(23-24): 3721-3725, 2018 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30348490
9.
Diphenylpyridylethanamine (DPPE)-based aminoheterocycles as cholesteryl ester transfer protein inhibitors.
Bioorg Med Chem Lett
; 24(3): 860-4, 2014 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24424134
10.
Corrigendum to "Identification of substituted benzothiazole sulfones as potent and selective inhibitors of endothelial lipase" [Bioorg. Med. Chem. Lett. 29 (2019) 1918-1921].
Bioorg Med Chem Lett
; 29(17): 2525, 2019 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31353296
11.
Identification of a potent and metabolically stable series of fluorinated diphenylpyridylethanamine-based cholesteryl ester transfer protein inhibitors.
Bioorg Med Chem Lett
; 22(20): 6503-8, 2012 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22995620
12.
Identification of Reversible Small Molecule Inhibitors of Endothelial Lipase (EL) That Demonstrate HDL-C Increase In Vivo.
J Med Chem
; 63(4): 1660-1670, 2020 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31990537
13.
Discovery of a Lead Triphenylethanamine Cholesterol Ester Transfer Protein (CETP) Inhibitor.
ACS Med Chem Lett
; 10(6): 911-916, 2019 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31223447
14.
Design and SAR of selective T-type calcium channel antagonists containing a biaryl sulfonamide core.
Bioorg Med Chem Lett
; 18(2): 474-8, 2008 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18160281
15.
2-Arylbenzoxazoles as novel cholesteryl ester transfer protein inhibitors: optimization via array synthesis.
Bioorg Med Chem Lett
; 18(8): 2640-4, 2008 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18374566
16.
Development of a Chemiluminescent ELISA Method for the Detection of Total Anti-Adeno Associated Virus Serotype 9 (AAV9) Antibodies.
Hum Gene Ther Methods
; 29(6): 237-250, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30351228
17.
Oral Delivery of Highly Lipophilic, Poorly Water-Soluble Drugs: Self-Emulsifying Drug Delivery Systems to Improve Oral Absorption and Enable High-Dose Toxicology Studies of a Cholesteryl Ester Transfer Protein Inhibitor in Preclinical Species.
J Pharm Sci
; 107(5): 1352-1360, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-29317226
18.
Sulfonylated Benzothiazoles as Inhibitors of Endothelial Lipase.
ACS Med Chem Lett
; 9(12): 1263-1268, 2018 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30613337
19.
PK/PD Disconnect Observed with a Reversible Endothelial Lipase Inhibitor.
ACS Med Chem Lett
; 9(7): 673-678, 2018 Jul 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30034599
20.
NMR structure of a potent small molecule inhibitor bound to human keratinocyte fatty acid-binding protein.
J Med Chem
; 49(16): 5013-7, 2006 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-16884313